Systemic hyperbaric oxygen therapy: lower-extremity wound healing and the diabetic foot

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Diabetic Lower Extremity Ulcers and Hyperbaric Oxygen Therapy

The conditions for which HBO is used are varied. However, diabetic lower extremity ulcers are one of those with a substantial number of research trials supporting its administration. It now forms part of the care package in many diabetic care facilities throughout the world for patients with diabetic lower extremity ulcers that are not responding to conventional treatment. The following pages w...

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IGF-1 Increases with Hyperbaric Oxygen Therapy and Promotes Wound Healing in Diabetic Foot Ulcers

Objectives. To investigate insulin-like growth factor I (IGF-1) levels in response to hyperbaric oxygen therapy (HBOT) for diabetic foot ulcers and to determine whether IGF-1 is a predictive indicator of wound healing in patients with diabetic foot ulcers. Design and Methods. We treated 48 consecutive patients with diabetic foot ulcers with HBOT. Alterations of IGF-1 levels in patients whose wo...

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Hyperbaric oxygen therapy for diabetic foot ulcers.

Foot ulcers are a common and devastating complication of diabetes. Many patients with diabetic foot ulcers experience significant disability and ultimately require amputation. Despite attentive management with multiple modalities including surgical debridement, relief of pressure, and other standard measures, many diabetic foot ulcers persist as chronic, nonhealing wounds. Hyperbaric oxygen (HB...

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Hyperbaric Oxygen Therapy for Diabetic Foot Wounds

“O ne must always hope when one is desperate, and doubt when one hopes.” Gustave Flaubert. Hyperbaric oxygen therapy (HBOT) has been promoted as an effective treatment for diabetic foot wounds, and the first controlled trial for this indication was reported (in Diabetes Care) over 20 years ago (1). Advocates have suggested that the experimentally demonstrated effects of HBOT on improving wound ...

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Hyperbaric oxygen and wound healing.

Problem wounds, which fail to respond to traditional medical and surgical therapy, can be challenging to the plastic surgeon. Surgical, outpatient, and inpatient wound care costs can be exorbitant. Indirect costs, such as those related to patient productivity, disability, and premature death, can also be significant. The underlying problem in failure of a wound to heal is usually hypoxia and in...

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2000

ISSN: 0149-5992,1935-5548

DOI: 10.2337/diacare.23.10.1551